Central Nervous System Infections in Childhood – EDITED BY PRATIBHA SINGHI, DIANE E GRIFFIN AND CHARLES R NEWTON
Edited by
PRATIBHA SINGHI
Professor and Chief, Pediatric Neurology and Neurodevelopment, Post
Graduate Institute of Medical Education and Research, Chandigarh, India
DIANE E GRIFFIN
University Distinguished Service Professor, Alfred and Jill Sommer Chair,
W Harry Feinstone Department of Molecular Biology and Immunology,
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
and
CHARLES R NEWTON
Professor of Psychiatry, St John’s College and Department of Psychiatry,
University of Oxford, UK; and Senior Clinical Researcher, Kenya Medical
Research Institute–Wellcome Trust Programme, Kilifi, Kenya
Infections constitute the largest group among life-threatening diseases in children particu-
larly in resource-poor areas of the world. However, infections are also an issue in resource-
rich countries where even diseases preventable by immunization, such as measles, have been
causing epidemics. Moreover, increase in population mobility has facilitated spreading of
infections, and imported infections in previously immunized populations are becoming
more frequent.
As in other topics in medicine, our knowledge on infectious diseases has been subject
to tremendous changes in the last decade: work on new vaccines, association of specific
infections with specific genotypes, emerging resistance to microorganisms, and the avail-
ability of new therapeutic agents and modalities call for frequent updates for all profession-
als working in this specialty. A clinician can perform an extensive search on an infectious
disorder using internet resources; however, it is rather time consuming and may not neces-
sarily be holistic. While it is unrealistic to cover all developments in one volume, this book
offers a concise source of the latest information on a large number of childhood central
nervous system infections. Each chapter is written by a specialist with personal experience
in these disorders and therefore provides pragmatic coverage of the topic. In addition to the
chapters on specific infections, those on general pathogenesis and principles of manage-
ment should be very useful in providing a basic understanding of the disease process and
the underlying approach to management, while the chapter on neuroimaging will enlighten
the clinician regarding the appropriate use of various techniques and interpretation of images
to provide diagnostic clues to several central nervous system infections.
This addition to the International Review of Child Neurology series is truly an inter-
national collaborative effort and is likely to be a great contribution to the commitment of
the International Child Neurology Association to education in child neurology.
Banu Anlar
Departments of Pediatrics and Pediatric Neurology
Hacettepe University
Ankara, Turkey